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Sorbitan Polyester Conjugates for Use in Stabilizing Water-In-oil Emulsions And Delivering Controlled Release of Bioactive Agents

生技與醫藥 醫藥

技術/專利摘要表

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摘要
A composition in a water-in-oil-in-water (W/O/W) emulsion is disclosed. The composition comprises: (a) a continuous aqueous phase, comprising H2O; (b) an oil phase or an oil shell, dispersed in the continuous aqueous phase; and (c) a hydrophilic polymer, stabilizing an interface between the continuous aqueous phase and the oil phase or the oil shell to form the water-in-oil-in-water (W/O/W) emulsion. The oil phase or the oil shell comprises: (i) oil; (ii) an internal aqueous phase, dispersed within the oil or the oil shell; and (iii) a lipophilic sorbitan-polyester conjugate, stabilizing an interface between the oil and the inner aqueous phase to form a water-in-oil (W/O) emulsion. The lipophilic sorbitan-polyester conjugate comprises: (1) sorbitan; and (2) poly(lactide-co-ε-caprolactone) or polylactic acid (polylactide), conjugated to the sorbitan.
資料類別
專利
資料編號
S11404P0009
發明人
所有人
國家衛生研究院(National Health Research Institutes)
所有人屬性
研究機構
技術成熟度
其他
上架日期
2025/04/01
交易方式
專利_讓售,專利_專屬授權,
刊登有效日期
2026/12/31
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專利保護情形

專利保護狀態
已獲證
申請國
美國
專利類別
發明(TW,CN)/特許(JP)/Utility(US)
申請號
US15/547,490
申請日期
2016/01/12
公告號
US10172945B2
公告日期
2019/01/08
專利權起算日
2019/01/08
專利權屆滿日
2036/01/12


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